Abstract: Biomedical argument mining (BAM) aims at automatically identifying the argumentative structure in biomedical texts. However, identifying and classifying argumentative relations (AR) between argumentative components (AC) is challenging since it not only needs to understand the semantics of ACs but also need to capture the interactions between them. We argue that entities can serve as bridges that connect different ACs since entities and their mentions convey significant semantic information in biomedical argumentation. For example, it is common that related AC pairs share a common entity. Capturing such entity information can be beneficial for the Relation Identification (RI) task. In order to incorporate this entity information into BAM, we propose an Entity Coreference and Co-occurrence aware Argument Mining (ECCAM) framework based on an edge-oriented graph model for BAM. We evaluate our model on a benchmark dataset and from the experimental results we find that our method improves upon state-of-the-art methods.