Abstract: Multilingual pretrained language models (mPLMs) acquire valuable, generalizable linguistic information during pretraining and have advanced the state of the art on task-specific finetuning. To date, only ~31 out of ~2,000 African languages are covered in existing language models. We ameliorate this limitation by developing SERENGETI, a set of massively multilingual language model that covers 517 African languages and language varieties. We evaluate our novel models on eight natural language understanding tasks across 20 datasets, comparing to 4 mPLMs that cover 4-23 African languages. SERENGETI outperforms other models on 11 datasets across the eights tasks, achieving 82.27 average F\_1. We also perform analyses of errors from our models, which allows us to investigate the influence of language genealogy and linguistic similarity when the models are applied under zero-shot settings. We will publicly release our models for research.{Anonymous link}